There have been several studies of the nutritional and metabolic status of children with autism, but each focused on study of only a few biomarkers. We hypothesize that nutritional insufficiency and metabolic imbalances may play a role in autism spectrum disorders (ASD). More recently the focus has shifted to the relationship between relative metabolic disturbances and developmental disorders, for example those associated with Attention Deficit Disorder, learning disorders, and intellectual development. However, nutritional status depends not only on intake, but also on digestion, absorption, metabolic processing, and metabolic demand.
Vitamins, minerals, and essential amino acids are, by definition, essential for human health, primarily due to their critical function as enzymatic cofactors for numerous reactions in the body, such as the production of neurotransmitters and fatty acid metabolism Historically attention has focused on inadequate intake of vitamins and minerals due to poor diet as a major contributing factor to many child health problems in the US and around the world, including anemia (low iron), hypothyroid (low iodine), scurvy (vitamin C deficiency), and rickets (calcium and/or vitamin D deficiency).
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